{"id":8717,"date":"2024-11-20T12:19:04","date_gmt":"2024-11-20T11:19:04","guid":{"rendered":"https:\/\/www.pica-berlin.de\/?p=8717"},"modified":"2024-11-20T12:19:09","modified_gmt":"2024-11-20T11:19:09","slug":"what-do-3-mcpd-and-2-chloroethanol-have-in-common","status":"publish","type":"post","link":"https:\/\/www.pica-berlin.de\/en\/news\/what-do-3-mcpd-and-2-chloroethanol-have-in-common\/","title":{"rendered":"What do 3-MCPD and 2-chloroethanol have in common?"},"content":{"rendered":"\n

Study on the alternative source of false positive findings for 2-chloroethanol in dietary supplements<\/strong><\/p>\n\n\n\n

A. Romanotto<\/mark>, D. Bertuola, B. Ramm<\/p>\n\n\n\n

With our research we could prove the clear relationship between the 2-chloroethanol (2-CE) findings and polyethylene glycol (PEG) or ethylene glycol (EG) presence especially in food supplement samples. With this we can now provide an explanation for 2-CE as a false positive or focus the differences in the analysis results when using different methods. It is known, that results of HS-GC-MS vs. GC-MS\/MS analyses, particularly in food supplements, often do not match or sometimes are contrary.<\/p>\n\n\n\n

Our study examined different combinations in applications of EG and PEG in the presence and absence of chloride ions for the formation of 2-CE. Before we tested and verified the development of 2-CE from EG and PEG in the injector of GC. In the next step freshly harvested dried and powdered dandelion root samples were differently treated with EG and PEG. Clear formation of 2-CE was observed, particularly after treating the samples with EG\/PEG in the presence of chloride ions (HCl) but also without HCl and measuring with GC-MSMS.<\/p>\n\n\n

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A. Romanotto, RAFA 2024<\/figcaption><\/figure><\/div>\n\n\n

PEG as a source for 2-CE in food supplements can now be considered as a ubiquitous compound. The most important sources of EG units include the following:<\/p>\n\n\n\n